--- title: One Year After Launch, Plasmidsaurus RNA-Seq Challenges RT-qPCR as the Standard for Routine Gene Expression Analysis description: Plasmidsaurus RNA-Seq reaches 9,000+ researchers in year one and adds built-in cell-line ID, mycoplasma screening and virtual qPCR analysis from $50 a sample. image: https://news.lifesciencenewswire.com/hubfs/Plasmidsaurus%20Lab%20-%20Headquarters%20South%20San%20Fransisco.jpg --- [![Life Science Newswire 2](https://news.lifesciencenewswire.com/hs-fs/hubfs/Life%20Science%20Newswire%202.png?width=203&height=60&name=Life%20Science%20Newswire%202.png "Life Science Newswire 2")](https://lifesciencenewswire.com/) - [Newsroom](https://news.lifesciencenewswire.com/newsroom) - [Back to the main site](https://lifesciencenewswire.com/) ![LSNewswire-main-header-banner-v2-1](https://news.lifesciencenewswire.com/hubfs/LSNewswire-main-header-banner-v2-1.jpg "LSNewswire-main-header-banner-v2-1") # Newsroom #### Categories ![Arrow](https://cdn2.hubspot.net/hubfs/3842749/ps4-Pack/sidebar.svg "Arrow") #### Subscribe![](https://cdn2.hubspot.net/hubfs/3842749/ps4-Pack/subscribe-rss-button.svg) ![](https://cdn2.hubspot.net/hubfs/3842749/ps4-Pack/close-button.svg) ### Choose a Category - 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[Pharma (119)](https://news.lifesciencenewswire.com/newsroom/tag/pharma) - [Pharmacy (5)](https://news.lifesciencenewswire.com/newsroom/tag/pharmacy) - [Research (47)](https://news.lifesciencenewswire.com/newsroom/tag/research) - [Veterinary (6)](https://news.lifesciencenewswire.com/newsroom/tag/veterinary) - [Water (8)](https://news.lifesciencenewswire.com/newsroom/tag/water) See all ### Subscribe to Email Updates - ##### SHARE - - - # [One Year After Launch, Plasmidsaurus RNA-Seq Challenges RT-qPCR as the Standard for Routine Gene Expression Analysis](https://news.lifesciencenewswire.com/newsroom/one-year-after-launch-plasmidsaurus-rna-seq-challenges-rt-qpcr-as-the-standard-for-routine-gene-expression-analysis) November 10, 2026 *With 9,000+ researchers adopting Plasmidsaurus RNA-Seq in its first year, the $50 transcriptome-wide sequencing service now adds built-in cell-line ID and mycoplasma QC screening alongside virtual qPCR analysis.* *![Plasmidsaurus Lab - Headquarters South San Fransisco](https://news.lifesciencenewswire.com/hs-fs/hubfs/Plasmidsaurus%20Lab%20-%20Headquarters%20South%20San%20Fransisco.jpg?width=626&height=417&name=Plasmidsaurus%20Lab%20-%20Headquarters%20South%20San%20Fransisco.jpg)* One year after launching its ultrafast RNA-Seq service, Plasmidsaurus has reached more than 9,000 researchers across 1,000+ institutions, processing hundreds of thousands of samples to date. Starting at $50 per sample and delivering results in three days, the service is making transcriptome-wide gene expression analysis increasingly accessible for routine, everyday research. As more scientists turn to RNA-Seq for experiments traditionally performed with targeted RT-qPCR, Plasmidsaurus continues to expand its platform with new quality control and analysis capabilities that make it easier for researchers to get more from every sequencing run. "We started Plasmidsaurus because we wanted to fundamentally change how science gets done," said Mark Budde, CEO and co-founder of Plasmidsaurus. "For too long, scientists have had to choose between speed and scale, spending countless hours designing primers and setting up plates just to measure a handful of genes. Plasmidsaurus RNA-Seq is a radically different approach to gene expression, but one that builds on the workflows researchers already know. Just one year in, we're seeing researchers embrace this approach and make transcriptome-wide analysis part of their everyday experiments." ## One Year of Growing Adoption That shift is already taking shape across academic and industrial research, with Plasmidsaurus RNA-Seq gaining traction among researchers at leading institutions and contributing to a growing body of published research: - **Institutional reach:** Adopted by researchers at NIH-funded institutions, NCI-designated cancer centers, and leading biopharmaceutical organizations. - **High-volume scale:** Hundreds of thousands of RNA-Seq samples processed since launch. - **Publication impact:** Cited in more than 100 peer-reviewed publications, including papers in *Nature*, *Science*, and *Nature Biotechnology*, with researchers from UCSF, UT Southwestern, Dana-Farber Cancer Institute, UC Berkeley, and a Nobel Prize-winning laboratory among those using the service. "Plasmidsaurus RNA-Seq helped me publish faster," said Heather Karner, a scientist at UCSF. Her team went from sample submission to publication in just 2.5 months with a study published in *Science Advances*, titled "Integrative analysis of mRNA stability regulation uncovers a metastasis-suppressive program in breast cancer." ## More Insight From Every RNA-Seq Run To make the transition from traditional RT-qPCR workflows easier, Plasmidsaurus developed virtual qPCR analysis tools that combine the familiarity of targeted gene expression analysis with the flexibility of transcriptome-wide data. Through its interactive analysis platform, researchers can create virtual qPCR panels using custom gene sets, cellular pathways, or targets from commercial RT-qPCR panels, then compare gene expression across samples. Unlike traditional RT-qPCR, these panels can be revisited, modified, or expanded to explore thousands of additional genes without repeating experiments. Plasmidsaurus has also introduced built-in cell-line identification and mycoplasma screening at no additional cost, giving researchers additional quality control insights from the same sequencing data. Both capabilities require no additional samples or sequencing steps. Mycoplasma screening is enabled by default for academic customers, while commercial customers can opt in through their account settings. To support larger and more complex studies, the platform has also introduced automated batch correction to help researchers account for technical variation across experiments and multiple sample submission timepoints. "When scaling transcriptome-wide screening across hundreds of plates and complex timelines, technical variation can mask critical biological insights," said Justin Blethrow, RNA Product Marketing Lead at Plasmidsaurus. "Our integrated batch correction removes these computational artifacts automatically. This allows researchers to pool data confidently across massive, longitudinal experiments without needing an internal bioinformatics team."   ## Making Routine RNA-Seq Accessible Plasmidsaurus RNA-Seq costs $50 per sample for academic researchers and $80 for commercial customers, including RNA extraction from cells, library preparation, shipping through Plasmidsaurus dropboxes, and bioinformatics analysis. Results are delivered in three days for samples shipped within the US or Europe and approximately one week elsewhere. With no minimum sample requirements or custom quotes, researchers can order online and submit samples at any of Plasmidsaurus's 1,300+ global dropboxes. Through a partnership with Genovis, researchers can also ship purified RNA preserved in SEQguard™ Dino Preserve at ambient temperature, eliminating the need for dry ice and cold-chain shipping. ## The Next Evolution of Transcriptomics Looking ahead, Plasmidsaurus is expanding its RNA-Seq platform with broader sample compatibility, additional built-in quality controls, and new automated analysis tools that help researchers get more from their sequencing data. The rapid evolution and growing adoption of Plasmidsaurus RNA-Seq reflect a broader shift in how researchers approach gene expression analysis: moving beyond single-purpose experiments toward transcriptome-wide data that can be revisited as new questions emerge. The future of RNA-Seq isn't just faster sequencing. It's making comprehensive gene expression insights accessible and easy to interpret, giving researchers new ways to build on existing data, inform future experiments, and accelerate discovery. To learn more about Plasmidsaurus RNA-Seq, visit[plasmidsaurus.com/rna](https://plasmidsaurus.com/rna). --- **About Plasmidsaurus** Plasmidsaurus is the sequencing infrastructure for modern biology. Founded by scientists, for scientists, it was built around a simple idea: fast sequencing changes how research gets done. With global drop-off locations and labs, round-the-clock operations, purpose-built automation, and integrated analysis tools, Plasmidsaurus delivers results researchers can trust and act on. From routine validation to complex DNA sequencing projects, scientists rely on Plasmidsaurus to keep discovery moving.   Categories: [Omics & Genetics](https://news.lifesciencenewswire.com/newsroom/tag/omics-genetics), [Biotechnology](https://news.lifesciencenewswire.com/newsroom/tag/biotechnology), [Computing & Technology](https://news.lifesciencenewswire.com/newsroom/tag/computing-it), [Drug Discovery & Development](https://news.lifesciencenewswire.com/newsroom/tag/drug-discovery-development) ##### Browse more news ## Recent releases #### [One Year After Launch, Plasmidsaurus RNA-Seq Challenges RT-qPCR as the Standard for Routine Gene Exp...](https://news.lifesciencenewswire.com/newsroom/one-year-after-launch-plasmidsaurus-rna-seq-challenges-rt-qpcr-as-the-standard-for-routine-gene-expression-analysis) November 10, 2026 With 9,000+ researchers adopting Plasmidsaurus RNA-Seq in its first year, the $50 transcriptome-wide sequencing service now adds built-in cell-line ID... ##### [READ MORE](https://news.lifesciencenewswire.com/newsroom/one-year-after-launch-plasmidsaurus-rna-seq-challenges-rt-qpcr-as-the-standard-for-routine-gene-expression-analysis) #### [Sciensus Appoints James Tugendhat OBE as Chief Executive Officer](https://news.lifesciencenewswire.com/newsroom/sciensus-appoints-james-tugendhat-obe-as-chief-executive-officer) October 28, 2026 Sciensus has appointed James Tugendhat OBE as Chief Executive Officer, bringing more than 20 years of leadership experience across healthcare and comp... ##### [READ MORE](https://news.lifesciencenewswire.com/newsroom/sciensus-appoints-james-tugendhat-obe-as-chief-executive-officer) #### [Takara Bio Europe Introduces GMP-Grade Cellartis® MSC EV Wonder™ to Support Clinical-Scale Extracell...](https://news.lifesciencenewswire.com/newsroom/takara-bio-europe-introduces-gmp-grade-cellartis-msc-ev-wonder-to-support-clinical-scale-extracellular-vesicle-production) October 28, 2026 Takara Bio Europe announces the introduction of a Good Manufacturing Practice (GMP)-grade version of Cellartis® MSC EV Wonder™, its defined, xeno-free... ##### [READ MORE](https://news.lifesciencenewswire.com/newsroom/takara-bio-europe-introduces-gmp-grade-cellartis-msc-ev-wonder-to-support-clinical-scale-extracellular-vesicle-production) ![LS-Newswire-reverse](https://news.lifesciencenewswire.com/hs-fs/hubfs/raw_assets/public/LifeScienceNewswire_June2020/images/LS-Newswire-reverse.png?width=150&name=LS-Newswire-reverse.png "LS-Newswire-reverse") Life Science Newswire is a division of BioStrata Ltd, with company registered address: 3rd Floor, 1 Ashley Road, Altrincham, Cheshire, England, WA14 2DT. 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