Over the last 20-30 years, hundreds of ligands have been reported in the literature with a number of these falling into the category of ‘privileged ligands’, those which offer a fair chance of success for a certain cross-coupling reaction. In palladium catalysed cross-coupling reactions, users should be aware of a number of potential issues, particularly when scaling up their process from gram to kilogram quantities. The video highlights some of these so that scientists can consider at a much earlier stage the measures they need to take to reduce later scale-up obstacles.
Dr Carin Seechurn, Sinocompound, commented, “We created this video series to help problem-solve some of the issues we see occurring most frequently in the industry. With more than a decade of experience behind us, we see customers encountering the same challenges time and time again, many of which can be avoided by taking the right steps early on. We’re keen to help our customers accelerate their route to market by sharing our expertise and through providing flexible, high quality ligands with a rapid turnaround time.”
Sinocompound is committed to providing educational support to customers and the wider industry. Further to the new video series, recent white papers explore the use of H₈-BINAP ligands and selected applications of adamantyl-containing phosphine ligands.
For more information and resources, please visit en.sinocompound.com
About Sinocompound
Sinocompound Catalysts Co., Ltd. is a global provider of advanced homogeneous catalysts and ligands for a range of pharmaceutical and fine chemical applications. The company’s proven process is built around cutting-edge technology, flexibility, and speed-of-response ensuring delivery at the scale required. Established partnerships across industry and academia enable the development of novel chemistry; helping customers accelerate their route to market.
Established in 2008 and with headquarters in Zhangjiagang, China, Sinocompound focuses on listening to customers and delivering the high-quality catalyst technology they require – including homo- and heterogeneous metal catalysts, ligands, high-purity electronic and custom synthesis service.